Vol. 42 Núm. 2 (2022)
Artículos de revisión

Potencialidades como antivirales de compuestos de origen marino: una revisión

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  • Elizabet Casanova-Nodarse,
  • Idania Rodeiro Guerra,
  • Liena de Regla Ponce Rey
Elizabet Casanova-Nodarse
Instituto de Ciencias del Mar, Loma 35, Alturas del Vedado, Plaza de la Revolución, La Habana, Cuba
Idania Rodeiro Guerra
Instituto de Ciencias del Mar, Loma 35, Alturas del Vedado, Plaza de la Revolución, La Habana, Cuba.
Liena de Regla Ponce Rey
Laboratorio de Virología. Departamento de Microbiología y Virología. Facultad de Biología. Universidad de La Habana. Calle 25 No. 455 entre J e I, Vedado. La Habana. Cuba.

Publicado 30-01-2023

Palabras clave

  • organismos marinos,
  • productos naturales,
  • actividad antiviral,
  • enfermedades virales,
  • fármacos

Cómo citar

Casanova-Nodarse, E., Rodeiro Guerra, I., & Ponce Rey, L. de R. (2023). Potencialidades como antivirales de compuestos de origen marino: una revisión . Revista De Investigaciones Marinas, 42(2), 67–91. Recuperado a partir de https://revistas.uh.cu/rim/article/view/1147

Derechos de autor 2023 Revista de Investigaciones Marinas

Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.

Resumen

A pesar del gran número de evidencias experimentales y el desarrollo de algunos productos, a la fecha, la inmensa mayoría de las enfermedades virales carece de tratamiento terapéutico y profiláctico, y continúan siendo un grave problema de salud. Varias han sido las fuentes descritas como reservorios de compuestos con actividad antiviral contra un amplio espectro de virus. La vasta extensión oceánica ha sido clasificada, en la década de 1980, como el mayor depósito de productos naturales a evaluar por su actividad como posibles drogas. Varios estudios han demostrado que los organismos marinos producen una variedad de compuestos, derivados del metabolismo primario o secundario, que pue- den poseer actividades antivirales y aplicaciones farmacéuticas. Esta revisión se propone abordar las tendencias de la investigación sobre los efectos antivirales in vitro e in vivo de organismos marinos en los últimos años, contra diferentes clases de patógenos virales en todo el mundo. Se consultaron varias bases de datos electrónicas, incluidas PubMed, Google Scholar, Journal of Virology y Journal of General Virology, en busca de artículos publicados en inglés que evaluaran la actividad antiviral de compuestos de origen marino. Los datos presentados en esta revisión destacan las potencialidades de compuestos deriva- dos de organismos marinos como fuentes de nuevos antivirales y abren nuevas vías para más investigaciones sobre este tema.

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